| GILEAD SCIENCES INC | 8.49 | 5,965 |
| AMGEN INC | 7.87 | 1,951 |
| REGENERON PHARMACEUTICALS | 7.70 | 689 |
| VERTEX PHARMACEUTICALS INC | 7.40 | 1,178 |
| ASTRAZENECA PLC-SPONS ADR | 3.87 | 3,714 |
| ALNYLAM PHARMACEUTICALS INC | 3.02 | 830 |
| BIOGEN INC | 2.23 | 932 |
| ILLUMINA INC | 2.16 | 1,000 |
| ARGENX SE - ADR | 2.06 | 205 |
| PROSHARES ULTRA NASD BIOTECH | 2.02 | 2,500 |
| UNITED THERAPEUTICS CORP | 1.61 | 290 |
| MODERNA INC | 1.59 | 2,399 |
| SANOFI-ADR | 1.44 | 1,872 |
| VIATRIS INC | 1.38 | 7,423 |
| NEUROCRINE BIOSCIENCES INC | 1.35 | 633 |
| INCYTE CORP | 1.35 | 1,206 |
| SUMMIT THERAPEUTICS INC | 1.24 | 4,552 |
| BIOMARIN PHARMACEUTICAL INC | 1.23 | 1,173 |
| SAREPTA THERAPEUTICS INC | 1.19 | 598 |
| BIONTECH SE-ADR | 1.15 | 614 |
| INSMED INC | 1.15 | 1,103 |
| MEDPACE HOLDINGS INC | 1.11 | 208 |
| ROYALTY PHARMA PLC- CL A | 1.10 | 2,739 |
| VAXCYTE INC | 1.07 | 796 |
| EXELIXIS INC | 0.91 | 1,748 |
| INTRA-CELLULAR THERAPIES INC | 0.84 | 662 |
| ASCENDIS PHARMA A/S - ADR | 0.84 | 385 |
| ROIVANT SCIENCES LTD | 0.79 | 4,425 |
| JAZZ PHARMACEUTICALS PLC | 0.73 | 386 |
| REVOLUTION MEDICINES INC | 0.71 | 1,038 |
| MADRIGAL PHARMACEUTICALS INC | 0.66 | 132 |
| HALOZYME THERAPEUTICS INC | 0.62 | 790 |
| TEMPUS AI INC | 0.59 | 922 |
| CYTOKINETICS INC | 0.56 | 734 |
| BLUEPRINT MEDICINES CORP | 0.56 | 404 |
| IONIS PHARMACEUTICALS INC | 0.52 | 975 |
| BRIDGEBIO PHARMA INC | 0.51 | 1,164 |
| NUVALENT INC-A | 0.48 | 392 |
| KRYSTAL BIOTECH INC | 0.47 | 195 |
| GUARDANT HEALTH INC | 0.46 | 814 |
| ADMA BIOLOGICS INC | 0.46 | 1,550 |
| ALKERMES PLC | 0.44 | 999 |
| APELLIS PHARMACEUTICALS INC | 0.44 | 813 |
| CRINETICS PHARMACEUTICALS IN | 0.44 | 557 |
| ARCELLX INC | 0.43 | 367 |
| AXSOME THERAPEUTICS INC | 0.43 | 326 |
| ULTRAGENYX PHARMACEUTICAL IN | 0.41 | 614 |
| AVIDITY BIOSCIENCES INC | 0.40 | 811 |
| SCHOLAR ROCK HOLDING CORP | 0.38 | 566 |
| VERACYTE INC | 0.37 | 540 |
| IMMUNOVANT INC | 0.37 | 952 |
| CRISPR THERAPEUTICS AG | 0.36 | 544 |
| RHYTHM PHARMACEUTICALS INC | 0.36 | 389 |
| PTC THERAPEUTICS INC | 0.34 | 482 |
| NOVOCURE LTD | 0.33 | 711 |
| MERUS NV | 0.31 | 468 |
| XENON PHARMACEUTICALS INC | 0.31 | 486 |
| VERONA PHARMA PLC - ADR | 0.30 | 427 |
| SPRINGWORKS THERAPEUTICS INC | 0.30 | 493 |
| ACADIA PHARMACEUTICALS INC | 0.30 | 1,117 |
| ALVOTECH SA | 0.30 | 1,454 |
| AMICUS THERAPEUTICS INC | 0.29 | 1,994 |
| DENALI THERAPEUTICS INC | 0.28 | 909 |
| JANUX THERAPEUTICS INC | 0.28 | 337 |
| TWIST BIOSCIENCE CORP | 0.28 | 374 |
| DYNE THERAPEUTICS INC | 0.26 | 691 |
| KYMERA THERAPEUTICS INC | 0.25 | 404 |
| ARROWHEAD PHARMACEUTICALS IN | 0.25 | 836 |
| PROTAGONIST THERAPEUTICS INC | 0.25 | 414 |
| VERICEL CORP | 0.24 | 269 |
| RECURSION PHARMACEUTICALS-A | 0.23 | 1,814 |
| EDGEWISE THERAPEUTICS INC | 0.23 | 556 |
| IOVANCE BIOTHERAPEUTICS INC | 0.22 | 1,901 |
| VERA THERAPEUTICS INC | 0.22 | 338 |
| IMMUNITYBIO INC | 0.21 | 4,885 |
| BEAM THERAPEUTICS INC | 0.21 | 500 |
| AKERO THERAPEUTICS INC | 0.21 | 488 |
| AGIOS PHARMACEUTICALS INC | 0.20 | 387 |
| AMNEAL PHARMACEUTICALS INC | 0.20 | 1,688 |
| APOGEE THERAPEUTICS INC | 0.20 | 264 |
| IDEAYA BIOSCIENCES INC | 0.20 | 508 |
| LIGAND PHARMACEUTICALS | 0.20 | 120 |
| FORTREA HOLDINGS INC | 0.20 | 649 |
| GERON CORP | 0.20 | 3,824 |
| HARMONY BIOSCIENCES HOLDINGS | 0.20 | 374 |
| NEWAMSTERDAM PHARMA CO NV | 0.20 | 503 |
| MANNKIND CORP | 0.19 | 1,931 |
| TARSUS PHARMACEUTICALS INC | 0.19 | 215 |
| WAVE LIFE SCIENCES LTD | 0.19 | 923 |
| MIRUM PHARMACEUTICALS INC | 0.18 | 275 |
| DISC MEDICINE INC | 0.18 | 185 |
| AMPHASTAR PHARMACEUTICALS IN | 0.17 | 306 |
| CG ONCOLOGY INC | 0.17 | 368 |
| SUPERNUS PHARMACEUTICALS INC | 0.17 | 291 |
| NOVAVAX INC | 0.15 | 1,000 |
| STRUCTURE THERAPEUTICS INC | 0.15 | 346 |
| INDIVIOR PLC | 0.14 | 743 |
| ARVINAS INC | 0.14 | 463 |
| 10X GENOMICS INC-CLASS A | 0.14 | 582 |
| NURIX THERAPEUTICS INC | 0.13 | 419 |
| SYNDAX PHARMACEUTICALS INC | 0.13 | 590 |
| BIOCRYST PHARMACEUTICALS INC | 0.13 | 1,093 |
| HARROW INC | 0.13 | 230 |
| DYNAVAX TECHNOLOGIES CORP | 0.13 | 661 |
| DAY ONE BIOPHARMACEUTICALS I | 0.12 | 647 |
| IMMUNOCORE HOLDINGS PLC-ADR | 0.12 | 258 |
| ARCUTIS BIOTHERAPEUTICS INC | 0.12 | 507 |
| PRAXIS PRECISION MEDICINES I | 0.12 | 102 |
| INTELLIA THERAPEUTICS INC | 0.12 | 618 |
| OCULAR THERAPEUTIX INC | 0.12 | 887 |
| SPYRE THERAPEUTICS INC | 0.12 | 320 |
| ARS PHARMACEUTICALS INC | 0.11 | 642 |
| XENCOR INC | 0.11 | 293 |
| ROCKET PHARMACEUTICALS INC | 0.11 | 577 |
| CENTESSA PHARMACEUTICALS-ADR | 0.11 | 405 |
| AVADEL PHARMACEUTICALS | 0.10 | 607 |
| AURINIA PHARMACEUTICALS INC | 0.10 | 766 |
| KINIKSA PHARMACEUTICALS INTE | 0.10 | 314 |
| TRAVERE THERAPEUTICS INC | 0.10 | 340 |
| VIR BIOTECHNOLOGY INC | 0.09 | 717 |
| INNOVIVA INC | 0.09 | 332 |
| ARDELYX INC | 0.09 | 1,150 |
| ANI PHARMACEUTICALS INC | 0.09 | 101 |
| ABCELLERA BIOLOGICS INC | 0.08 | 1,548 |
| ADAPTIVE BIOTECHNOLOGIES | 0.08 | 699 |
| ARRIVENT BIOPHARMA INC | 0.08 | 184 |
| ANAVEX LIFE SCIENCES CORP | 0.08 | 381 |
| GRIFOLS SA-ADR | 0.08 | 651 |
| CUREVAC NV | 0.08 | 1,194 |
| ENLIVEN THERAPEUTICS INC | 0.08 | 211 |
| ZYMEWORKS INC | 0.08 | 358 |
| TYRA BIOSCIENCES INC | 0.07 | 275 |
| PLIANT THERAPEUTICS INC | 0.07 | 320 |
| PACIRA BIOSCIENCES INC | 0.07 | 248 |
| GENMAB A/S -SP ADR | 0.07 | 213 |
| KURA ONCOLOGY INC | 0.07 | 538 |
| COLLEGIUM PHARMACEUTICAL INC | 0.07 | 166 |
| CULLINAN THERAPEUTICS INC | 0.07 | 407 |
| COGENT BIOSCIENCES INC | 0.06 | 512 |
| KEROS THERAPEUTICS INC | 0.06 | 245 |
| IRONWOOD PHARMACEUTICALS INC | 0.06 | 833 |
| GRAIL INC | 0.06 | 187 |
| CASTLE BIOSCIENCES INC | 0.06 | 122 |
| ORUKA THERAPEUTICS INC | 0.06 | 191 |
| LENZ THERAPEUTICS INC | 0.06 | 149 |
| MARAVAI LIFESCIENCES HLDGS-A | 0.06 | 643 |
| PROTHENA CORP PLC | 0.06 | 286 |
| UNIQURE NV | 0.06 | 196 |
| RAPPORT THERAPEUTICS INC | 0.06 | 199 |
| ENTRADA THERAPEUTICS INC | 0.06 | 203 |
| TECTONIC THERAPEUTIC INC | 0.06 | 80 |
| STOKE THERAPEUTICS INC | 0.05 | 289 |
| PHATHOM PHARMACEUTICALS INC | 0.05 | 405 |
| REPLIMUNE GROUP INC | 0.05 | 271 |
| SANA BIOTECHNOLOGY INC | 0.05 | 1,674 |
| MIND MEDICINE MINDMED INC | 0.05 | 400 |
| OMEROS CORP | 0.05 | 316 |
| HUMACYTE INC | 0.05 | 594 |
| 89BIO INC | 0.05 | 403 |
| CARGO THERAPEUTICS INC | 0.05 | 251 |
| ANNEXON INC | 0.05 | 581 |
| ARCTURUS THERAPEUTICS HOLDIN | 0.04 | 127 |
| ARBUTUS BIOPHARMA CORP | 0.04 | 780 |
| ALTIMMUNE INC | 0.04 | 387 |
| CORMEDIX INC | 0.04 | 330 |
| BICYCLE THERAPEUTICS PLC-ADR | 0.04 | 185 |
| ASTRIA THERAPEUTICS INC | 0.04 | 307 |
| EYEPOINT PHARMACEUTICALS INC | 0.04 | 260 |
| GALAPAGOS NV-SPON ADR | 0.04 | 93 |
| MONTE ROSA THERAPEUTICS INC | 0.04 | 335 |
| EVOLUS INC | 0.04 | 257 |
| ORIC PHARMACEUTICALS INC | 0.04 | 279 |
| PACIFIC BIOSCIENCES OF CALIF | 0.04 | 1,368 |
| PHIBRO ANIMAL HEALTH CORP-A | 0.04 | 118 |
| MINERALYS THERAPEUTICS INC | 0.04 | 210 |
| MESOBLAST LTD- SPON ADR | 0.04 | 135 |
| MAXCYTE INC | 0.04 | 580 |
| RELAY THERAPEUTICS INC | 0.04 | 592 |
| CARTESIAN THERAPEUTICS INC | 0.04 | 139 |
| THERAVANCE BIOPHARMA INC | 0.04 | 264 |
| TOURMALINE BIO INC | 0.04 | 104 |
| THIRD HARMONIC BIO INC | 0.04 | 206 |
| VERVE THERAPEUTICS INC | 0.04 | 407 |
| ZEVRA THERAPEUTICS INC | 0.04 | 291 |
| Y-MABS THERAPEUTICS INC | 0.03 | 223 |
| XERIS BIOPHARMA HOLDINGS INC | 0.03 | 600 |
| ALPHA TEKNOVA INC | 0.03 | 226 |
| TANGO THERAPEUTICS INC | 0.03 | 544 |
| TAYSHA GENE THERAPIES INC | 0.03 | 997 |
| ACELYRIN INC | 0.03 | 498 |
| TERNS PHARMACEUTICALS INC | 0.03 | 292 |
| SAVARA INC | 0.03 | 692 |
| SAGE THERAPEUTICS INC | 0.03 | 320 |
| SIGA TECHNOLOGIES INC | 0.03 | 334 |
| REGENXBIO INC | 0.03 | 212 |
| PERSONALIS INC | 0.03 | 299 |
| PRIME MEDICINE INC | 0.03 | 498 |
| MEIRAGTX HOLDINGS PLC | 0.03 | 256 |
| NEUMORA THERAPEUTICS INC | 0.03 | 880 |
| OMNIAB INC | 0.03 | 594 |
| ERASCA INC | 0.03 | 700 |
| ESPERION THERAPEUTICS INC | 0.03 | 834 |
| CORVUS PHARMACEUTICALS INC | 0.03 | 272 |
| AURA BIOSCIENCES INC | 0.03 | 211 |
| AUTOLUS THERAPEUTICS PLC | 0.03 | 719 |
| ATEA PHARMACEUTICALS INC | 0.03 | 479 |
| CODEXIS INC | 0.03 | 344 |
| ABSCI CORP | 0.03 | 487 |
| ANAPTYSBIO INC | 0.03 | 130 |
| ALUMIS INC | 0.03 | 200 |
| AMYLYX PHARMACEUTICALS INC | 0.02 | 309 |
| AMARIN CORP PLC -ADR | 0.02 | 1,863 |
| ARTIVA BIOTHERAPEUTICS INC | 0.02 | 103 |
| AQUESTIVE THERAPEUTICS INC | 0.02 | 386 |
| AC IMMUNE SA | 0.02 | 367 |
| ALLOGENE THERAPEUTICS INC | 0.02 | 705 |
| C4 THERAPEUTICS INC | 0.02 | 299 |
| COMPASS PATHWAYS PLC | 0.02 | 216 |
| DESIGN THERAPEUTICS INC | 0.02 | 240 |
| 4D MOLECULAR THERAPEUTICS IN | 0.02 | 228 |
| FOGHORN THERAPEUTICS INC | 0.02 | 235 |
| INHIBRX BIOSCIENCES INC | 0.02 | 62 |
| KALVISTA PHARMACEUTICALS INC | 0.02 | 176 |
| ITEOS THERAPEUTICS INC | 0.02 | 162 |
| LARIMAR THERAPEUTICS INC | 0.02 | 270 |
| LEXEO THERAPEUTICS INC | 0.02 | 140 |
| OLEMA PHARMACEUTICALS INC | 0.02 | 280 |
| PDL BIOPHARMA INC | 0.02 | 875 |
| NEUROGENE INC | 0.02 | 63 |
| PRECIGEN INC | 0.02 | 1,193 |
| RIGEL PHARMACEUTICALS INC | 0.02 | 75 |
| SILENCE THERAPEUTICS PLC-ADR | 0.02 | 199 |
| TEVOGEN BIO HOLDINGS INC | 0.02 | 741 |
| TREVI THERAPEUTICS INC | 0.02 | 326 |
| UROGEN PHARMA LTD | 0.02 | 119 |
| VANDA PHARMACEUTICALS INC | 0.02 | 321 |
| VOYAGER THERAPEUTICS INC | 0.02 | 225 |
| 2SEVENTY BIO INC | 0.01 | 218 |
| SUTRO BIOPHARMA INC | 0.01 | 349 |
| TSCAN THERAPEUTICS INC | 0.01 | 208 |
| SOLID BIOSCIENCES INC | 0.01 | 169 |
| SCPHARMACEUTICALS INC | 0.01 | 212 |
| NKARTA INC | 0.01 | 299 |
| MERSANA THERAPEUTICS INC | 0.01 | 524 |
| MACROGENICS INC | 0.01 | 252 |
| PEPGEN INC | 0.01 | 138 |
| LEXICON PHARMACEUTICALS INC | 0.01 | 860 |
| LYELL IMMUNOPHARMA INC | 0.01 | 1,141 |
| KYVERNA THERAPEUTICS INC | 0.01 | 183 |
| IGM BIOSCIENCES INC | 0.01 | 144 |
| INOZYME PHARMA INC | 0.01 | 272 |
| FATE THERAPEUTICS INC | 0.01 | 482 |
| EDITAS MEDICINE INC | 0.01 | 435 |
| BIOMEA FUSION INC | 0.01 | 162 |
| CLIMB BIO INC | 0.01 | 285 |
| ALECTOR INC | 0.01 | 379 |
| ACRIVON THERAPEUTICS INC | 0.01 | 132 |
